Melatonin is a natural hormone produced by the brain through the pineal gland. Its level of circulation in the body varies during the day depending on environmental factors.
Melatonin release and synthesis are inhibited by light and stimulated by darkness, suggesting that the element plays an integral role in circadian rhythm (biochemical, physiological and behavioral processes based on a 24-hour cycle) in the body.
It has adaptogenic, sedative, hypnotic effect.
Normalizes circadian rhythms. Increases concentrations of GABA and serotonin in the midbrain and hypothalamus, changes the activity of pyridoxal kinase involved in the synthesis of GABA, dopamine and serotonin. GABA is known to be an inhibitory mediator in the CNS, and a decrease in the activity of serotonergic mechanisms may be important in the pathogenesis of depressive states and disorders.
Regulates the sleep-wake cycle, daily changes in locomotor activity and body temperature, has a positive effect on the intellectual and mental functions of the brain, on the emotional and personality sphere. Contributes to the organization of the biological rhythm and normalization of night sleep. Improves sleep quality, reduces the frequency of headaches, dizziness, and improves mood. It accelerates falling asleep, reduces the frequency of night awakenings, improves feelings after waking up in the morning, does not cause a feeling of lethargy, brokenness and fatigue upon awakening. Makes dreams more vivid and emotionally intense.
Adapts the body to rapid change of time zones, reduces stress reactions, regulates neuroendocrine functions.
It has immunostimulatory and antioxidant properties.
The main physiological effect of melatonin is inhibition of gonadotropin secretion. In addition, the secretion of other adenohypophysis hormones – corticotropin, TTG, and STH – decreases, but to a lesser extent.
Melatonin secretion is subject to a circadian rhythm, which, in turn, determines the rhythmicity of gonadotropic effects and sexual function. The synthesis and secretion of melatonin depend on light – excess light inhibits its formation, while lower light increases the synthesis and secretion of the hormone. In humans, the night hours account for 70% of the daily production of melatonin.
Take 1/2 tablet two hours before bedtime
Reviews
There are no reviews yet.